The Web & Information Systems Engineering (WISE) Laboratory is a research unit of the department of Computer Science of the Vrije Universiteit Brussel. WISE is headed by Professor Olga De Troyer and Professor Beat Signer.

The activities of WISE concentrate on innovative information systems, such as next generation web applications, mobile and context-aware applications, interactive paper and cross-media solutions as well as the multimodal and multi-touch interaction with these mixed-media information spaces. We develop new engineering methodologies, tools and software frameworks for the rapid prototyping and efficient realization of innovative information environments.

There is a strong emphasis on conceptual modeling and design, semantics, reasoning on designs, adaptation and personalization, localization and globalization, accessibility, and usability in general. Important technologies used in this context are Semantic Web technologies, Web 2.0 technologies, ontologies, graphical and visual design languages, and design patterns.

Important application domains are Web applications, augmented and virtual reality, games and serious games, and e-learning.